Cisplatin and pemetrexed for lung cancer
WebMay 14, 2024 · Previous phase III studies have demonstrated the efficacy of postoperative cisplatin-based adjuvant chemotherapy for the treatment … WebNov 20, 2008 · A phase II multicentre study of ziv-aflibercept in combination with cisplatin and pemetrexed in patients with previously untreated advanced/metastatic non-squamous non-small cell lung cancer. Br J Cancer. 2014 Feb 4;110(3):602-8. doi: 10.1038/bjc.2013.735.
Cisplatin and pemetrexed for lung cancer
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WebDec 31, 2014 · In patients with adenocarcinoma, overall survival was statistically superior for cisplatin/pemetrexed versus cisplatin/gemcitabine (n=847; 12.6 v 10.9 months)." And from the summary: "Patients who have advanced disease, are performance status 0-1, have predominantly nonsquamous WebComparison of Carboplatin Plus Pemetrexed Followed by Maintenance Pemetrexed With Docetaxel Monotherapy in Elderly Patients With Advanced Nonsquamous Non–Small Cell Lung Cancer: A Phase 3 Randomized Clinical Trial …
WebDec 8, 2024 · Nivolumab, Cisplatin, and Pemetrexed Disodium or Gemcitabine Hydrochloride in Treating Patients With Stage I-IIIA Non-small Cell Lung Cancer That Can Be Removed by Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. WebMar 24, 2024 · The study enrolled 305 patients to receive Keytruda or platinum-based chemotherapy: paclitaxel+carboplatin, pemetrexed+carboplatin, pemetrexed+cisplatin, gemcitabine+carboplatin, or gemcitabine+cisplatin. Patients treated with platinum based chemotherapy had the option of crossing over to Keytruda upon disease progression.
WebResults: When the PEP was combined with cisplatin and tested against solid tumor cell lines and the CCRF-CEM leukemia cell line, there was a modest synergistic effect. A … WebKenmotsu H, Yamamoto N, Yamanaka T, et al. Randomized Phase III study of pemetrexed plus cisplatin versus vinorelbine plus cisplatin for completely resected Stage II to IIIA non-squamous non-small cell lung cancer. J Clin Oncol. 2024; 38(19): 2187 -2196 2. Ciuleanu T, Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care
Webpemetrexed versus cisplatin-gemcitabine in advanced non-small-cell lung cancer. Ann Oncol 2010;21(3):55661.- 3. Ciuleanu T, Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet …
WebDec 1, 2024 · Paz-Ares L, de Marinis F, Dediu M, et al. Maintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): a double-blind, phase 3, randomised controlled trial. the project whichWebJun 2, 2024 · Adjuvant treatment with pemetrexed/cisplatin was not found to be superior to vinorelbine/cisplatin, but was better tolerated, in patients with non-squamous non–small-cell lung cancer (NS-NSCLC), according to new data from the JIPANG phase III study that were presented at the 2024 American Society of Clinical Oncology (ASCO) Annual … signature health brocktonWebPemetrexed and cisplatin is a combination treatment used to treat non-small cell lung cancer and pleural mesothelioma. It is best to read this information with our general … signature healthcare at home bellingham wahttp://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Lung/LUAVPP_Protocol.pdf signature healthcare ait programWebJul 1, 2024 · Background/aim: Cisplatin combined with pemetrexed disodium heptahydrate (pemetrexed) is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer. However, its growth-inhibitory effects on KRAS-dependent lung cancer as monotherapy and combination therapy are not well understood. the project westcliffWebDay 1: Bevacizumab 7.5mg/kg IV + cisplatin 75mg/m 2 IV + pemetrexed 500mg/m 2 IV. Repeat cycle every 3 weeks for 4 cycles, followed by: Day 1: Bevacizumab 7.5mg/kg IV + pemetrexed 500mg/m 2 IV. signature healthcare at mallard bayWebNov 1, 2024 · The lung cancer stage will be determined according to the 8th edition of the International Association for the Study of Lung Cancer (IASLC) Tumor, Node, Metastasis (TNM) staging system for lung cancer. ... Modification of carboplatin or cisplatin, and pemetrexed doses will be done according to the local guidelines of National Taiwan … signature healthcare at hillcrest owensboro