Webb11 okt. 2024 · Here we present the generation and characterization of transgenic mice expressing the sensitive red GECI jRGECO1a, driven by the Thy1 promoter. Four … Thy1 expression comes on when endothelial cells are activated. It has been shown to interact with the leukocyte integrin Mac1 (CD11b/CD18) and may play a role in leukocyte homing and recruitment. Modulating fibrosis. Role of Thy-1 in fibrosis and fibroblast differention may have some tissue variation. Visa mer Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a Visa mer The antigen Thy-1 was the first T cell marker to be identified. Thy-1 was discovered by Reif and Allen in 1964 during a search for … Visa mer The 25-kDa core protein (excluding the heavy glycosylation) of rodent Thy-1 is 111 or 112 amino acids in length, and is N-glycosylated at three sites (In contrast to only two glycosylation sites for human Thy-1). The 162aa (murine, 161 for human) Thy1 … Visa mer Thy1 expression varies between species. Amongst the cells reported to generally express Thy-1 are thymocytes (precursor of T cells in the thymus) & CD34(+) prothymocytes; Visa mer Thy-1 has been conserved throughout vertebrate evolution and even in some invertebrates, with homologs described in many species like squid, frogs, chickens, mice, rats, dogs, and humans. The Thy-1 gene is located at human chromosome 11q22.3 … Visa mer Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. Thy1 in most species has 3 N-glycosylation … Visa mer As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in the cell membrane. In case of neurons it is known to be expressed strongly in the mature axon. The Visa mer
Characterization of transgene expression and Cre recombinase
WebbThy-1 is highly expressed in ovarian cancer cells, especially serous adenocarcinoma. Bioinformatic analysis of ovarian tissue databases demonstrated higher expression of Thy-1 in cancerous versus... WebbArticle Snippet: The Thy1-EGFP transgene mice expressing enhanced green fluorescent protein (EGFP) under the control of a modified regulatory region of the mouse thy1.2 gene promoter (containing the sequences required for neuronal expression but lacking the sequences required for expression in non-neural cells) were obtained from The Jackson … marilyn monroe as norma jean
Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging …
Webb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its related pathways are Metabolism of proteins and Integrin Pathway . Gene Ontology (GO) annotations related to this gene include protein kinase binding and GTPase activator … Webb9 apr. 2024 · Thy1 is a novel lymphatic vessel expressed gene, and has a potential role in the cell adhesion processes required for tumor progression and inflammation Findings suggest that Thy-1 down-regulates TNF-alpha-activated gene expression via interfering with SFK- and NF-kappaB-mediated transactivation. WebbThy1 promoter. To linearize plasmid and remove vector sequences, EcoRI + PvuI , or alternatively NotI + PvuI are used ... Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Livet J, Weissman TA, Kang H, Draft RW, Lu J, Bennis RA, Sanes JR, Lichtman JW ... natural reserves in uae